後生元 /益生素 (Postbiotics)

GLP-1 Nutrition Support

GLP-1 Nutrition Support

GLP-1是什麼?

GLP-1(Glucagon-Like Peptide-1,胰高血糖素樣肽-1)是一種由人體腸道細胞分泌的腸促胰素(Incretin),在血糖調節和能量代謝中扮演重要角色。

由於GLP-1在血糖調節中的重要作用,它成為2型糖尿病治療的一個重要目標。GLP-1受體激動劑(GLP-1 receptor agonists)是用於治療2型糖尿病的一類藥物,它們可以模仿GLP-1的作用,促進胰島素分泌、抑制胰高血糖素分泌、減少食慾和延緩胃排空。

GLP-1 Nutrition Support

GLP-1的減肥功效

GLP-1(Glucagon-Like Peptide-1,胰高血糖素樣肽-1)受體激動劑能夠模仿人體自然分泌的GLP-1,從而實現減重效果。以下是GLP-1受體激動劑在減肥中的功效:

減肥功效

  1. 降低食慾
  2. 增加飽腹感
  3. 促進脂肪分解
  4. 血糖控制
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GLP-1

副作用

儘管GLP-1受體激動劑有很多優點,但它們也可能帶來一些副作用:

  1. 胃腸道反應
  2. 低血糖
  3. 胰腺炎
  4. 膽囊疾病
  5. 腎功能影響

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Reference:

  • Insights into a possible role of glucagon-like peptide-1 receptor agonists in the treatment of depression Special Issue: Review Open access Published: 18 May 2021 Volume 73, pages 1020–1032, (2021)
  • GLP-1 and the kidney: from physiology to pharmacology and outcomes in diabetes Marcel H. A. Muskiet, Lennart Tonneijck, Mark M. Smits, Michaël J.B. van Baar, Mark H. H. Kramer, Ewout J. Hoorn, Jaap A. Joles & Daniël H. van Raalte Nature Reviews Nephrology volume 13, pages605–628 (2017)
  • Cardiovascular benefits of GLP-1 agonists in type 2 diabetes: A comparative review Article Full-text available Aug 2018 James G. Boyle Rachel Livingstone John R Petrie
  • Effects of GLP-1 receptor agonists on myokine levels and pro-inflammatory cytokines in patients with type 2 diabetes mellitus Article Full-text available Jul 2021 Valentina Guarnotta Maria J. Bianco Enrica Vigneri[...] Carla Giordano
  • Glucagon-like peptide-1 (GLP-1) receptor agonists and cardiovascular events in patients with type 2 diabetes mellitus: A meta-analysis of double-blind, randomized, placebo-controlled clinical trials Preprint Full-text available Feb 2020 Jing Qin Li Song